TKI-PPP grants awarded to Amsterdam UMC researchers

Seventeen researchers of Amsterdam UMC have been awarded a TKI-PPP grant between € 300.000 and € 750.000 to perform a research project in collaboration with an industrial party. The funding is provided by the NL government (Ministry of Economic Affairs) through the Rijksdienst voor Ondernemend Nederland (RVO) and the Topconsortium voor Kennis en Innovatie Life Sciences & Health (TKI-LSH, a.k.a. Health-Holland).

About the TKI-PPI grant
In September 2020 the call for the Amsterdam UMC TKI grant 2020-2021 opened. The Amsterdam UMC TKI grants for PPP projects are available to all Amsterdam UMC researchers and aims to them to perform more research projects in collaboration with companies in Public-Private Partnerships (PPP).

As of last year the TKI grant procedures from AMC and VUmc are combined. This means that the grant amounts available to both UMC’s are put together, adding up to an amount of approximately 8.5 million euros to be awarded to our best PPP-research proposals.

Awarded projects
Knowing that applying requires a serious effort of the researchers, we were delighted to receive a total of 50 applications. The jury first selected 27 final proposals to go to the final round, after which the following 17 proposals could be awarded:

ADAPT-PD
Dysfunctional adaptive immune responses drive the disease progression of Parkinson’s disease
dr. Wilma D.J. van de Berg, Amsterdam UMC, location VUmc
Subsidy of € 420.150

AI-DBS
Applying Personalized Neuromodulation using Neural ‘Fingerprints’
dr. Martijn Beudel, Amsterdam UMC, location AMC
Subsidy of € 510.320

COMFORTHOD
An innovative tool to diagnose loosening of a total knee arthroplasty
dr. ir. Leendert Blankevoort , Amsterdam UMC, location AMC
Subsidy of € 656.892

CLOSIT
CLL Lymph node Organoids for Screens and Intelligent Testing
prof. dr. Eric Eldering, Amsterdam UMC, location AMC
Subsidy of € 679.400

INFLUVAX
Novel approach for evolution-proof influenza vaccination
prof. dr. Arjan W. Griffioen, Amsterdam UMC, location VUmc
Subsidy of € 660.800

SYNCH
Combining SYNbiotics with Conditioned FMT – tapping into the potential of the gut microbiome to treat non-alcoholic steatoHepatitis
dr. A.G. (Onno) Holleboom, Amsterdam UMC, location AMC
Subsidy of € 436.080

AD-REPEAT
Comparison of genetic repeat expansions between Alzheimer’s Disease patients and cognitively healthy centenarians
dr. Henne Holstege, Amsterdam UMC, location VUmc
Subsidy of € 640.000

PA-MRI in AD
Pathological sensitivity of MRI biomarkers in AD
dr. Laura E. Jonkman, Amsterdam UMC, location VUmc
Subsidy of € 462.031

3D-IRI
A novel 3D dual-cell perfusion model as tool to identify  and validate potential druggable targets to reduce Ischemia Reperfusion Injury (3D-IRI)
dr. Jeffrey Kroon, Amsterdam UMC, location AMC
Subsidy of € 339.570

MARVY
Gamechanger: Development of MRI based endovasculAR procedures for Vascular surgerY
prof. dr. ir. Aart J. Nederveen, Amsterdam UMC, location AMC
Subsidy of € 748.040

Compound screening and validation to reduce mutant huntingtin levels
dr. Eric Reits, Amsterdam UMC, location AMC
Subsidy of € 440.481

AMESMC
Automated Strabismus Measurement
dr. L.J. (René) van Rijn, Amsterdam UMC, location VUmc
Subsidy of € 339.000

MED-aNaL
MEthylation Diagnostics for minimally-invasive aNaL cancer screening
prof. dr. Renske D.M. Steenbergen, Amsterdam UMC, location VUmc
Subsidy of € 423.105

ULTRADOC
Ultrafast optical spectroscopy for depth resolved optical biopsy
prof. dr. ir. H.J.C.M. (Dick) Sterenborg, Amsterdam UMC, location AMC
Subsidy of € 437.650

Cell-PET
Imaging of NK cells with PET: towards better understanding of CAR-NK and NK cell therapy
dr. Danielle Vugts, Amsterdam UMC, location VUmc
Subsidy of € 396.200

AI-IMPACT
Repurposing and discovery of multi-target kinase inhibitors against brain tumors
dr. Bart Westerman, Amsterdam UMC, location VUmc
Subsidy of € 688.598

The Toxicity atlas
Application of artificial intelligence to predict toxicities of combination therapies
dr. Bart Westerman, Amsterdam UMC, location VUmc
Subsidy of € 500.000

We wish all winning applicants lots of success performing their projects!